Polacrilex
Ion-exchanging resin Polacrilex®
Chemical description: Polacrilex® is copolymerized by divinylbenzene (DVB) with methylacrylic acid or phenol polyamine. (The product meets USP/NF, Eur., Ph., JP pharmacopoeia standards).
Brand:
General name
|
Specification
|
Plasma form
|
Acid-base
|
Ingredient
|
Characteristics application
|
--
|
|
Cation
|
--
|
--
|
--
|
| Polacrilin |
IRP-64
DMF# 12903
|
H+ |
Weak acid |
Methacrylic acid and DVB |
Taste masker, stabilizer, carrier for cation drugs |
| Polacrilin |
IRP-88
DMF# 19264
|
K+ |
Weak acid |
Methacrylic acid and DVB |
Disintegrant, taste-mask agent, stabilizer |
| Polacrilin sodium |
IRP-69
DMF# 12355
|
Na+ |
Strong acid |
Stryene and DVB |
Sustained release preparation, stabilizer (applicable to alkali or saline) |
--
|
Duolite
|
--
|
--
|
--
|
--
|
| -- |
AP-143 |
Free alkali |
Strong acid |
Phenol polyamine and DVB |
Sustained release preparation, carrier for anion drug (acid) |
Characteristics application:
IRP-88 Polac phosphate and potassium is the cation exchanging resin used as tablet disintegrant in oral drug preparation.
Amberlite® IRP-69, Duolite® AP143 ion exchanging resin is used as drug stabilizer to mask or improve drug taste, or sustained release agent, or rather as drug carrier. Some polarcrilin resins can also be applied in the analysis and production of drug and food;
Common concentration range is 2%-10%.
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