Magnesium aluminum silicate Neusilin®
Chemical description: Neusilin is a kind of honeycomb structured mineral salt filler composed of Ai2O3: 29.1-35.5%, MgO: 11.4-14.0% and SiO2: 29.2-35.60%.
Brand: Neusilin®
General name
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Specification
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Mean diameter
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Moisture %
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Bulk density g/ml
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Magnesium aluminum silicate Neusilin
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US2
DMF# 12893
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60-120 渭m
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< 7
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0.13-0.18
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Magnesium aluminum silicate Neusilin
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UFL2
DMF# 12893
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2-8 渭m
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< 7
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0.06-0.11
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Magnesium aluminum silicate Neusilin
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10-20 渭m
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<5
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0.25-0.33
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Characteristics application:
Neusilin's high porosity has excellent absorptivity, besides enhancing tablet hardness and improving powder flowability, it also prevent hygroscopic drugs from deliquescene.
Compared with colloidal silicon dioxide, Neusilin maintains excellent long-term stability and flowability while absorbing oily substance, enabling liquid medicine to be solidified.
Neusilin solves low melting point and moisture absorptive drug's tablets problem, 3-5% addition can improve product long-term stability.
Neusilin acts as ideal sorption carrier in the preparation process of hot-melt extrusion, lyosorption, emulsification system and solid liposome nanoparticle.
The product can improve poorly water soluble drug's dissolution and bio-availability. Solid dispersion's sorption carrier common type: US2 or USL2
Adhesion, disintegration: 5-15%, flow aid: 0.5-5.0%, sorption carrier: 20-50%, filler: 30-90%
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